gcodeml: A Grid-enabled Tool for Detecting Positive Selection in Biological Evolution

Détails

Ressource 1Télécharger: BIB_542C5BE6E2B7.P001.pdf (327.77 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_542C5BE6E2B7
Type
Partie de livre
Collection
Publications
Titre
gcodeml: A Grid-enabled Tool for Detecting Positive Selection in Biological Evolution
Titre du livre
HealthGrid Applications and Technologies Meet Science Gateways for Life Sciences
Auteur(s)
Moretti S., Murri R., Maffioletti S., Kuzniar A., Castella B, Salamin N., Robinson-Rechavi M., Stockinger H.
Editeur
IOS Press Books online
ISBN
978-1-61499-053-6
Statut éditorial
Publié
Date de publication
2012
Editeur scientifique
Glatard T, Silverstein J
Volume
175
Série
Studies in Health Technology and Informatics
Pages
59-68
Langue
anglais
Notes
ArXiv: http://arxiv.org/abs/1203.309 pas encore index; dans PubMed
Résumé
One of the important questions in biological evolution is to know if certain changes along protein coding genes have contributed to the adaptation of species. This problem is known to be biologically complex and computationally very expensive. It, therefore, requires efficient Grid or cluster solutions to overcome the computational challenge. We have developed a Grid-enabled tool (gcodeml) that relies on the PAML (codeml) package to help analyse large phylogenetic datasets on both Grids and computational clusters. Although we report on results for gcodeml, our approach is applicable and customisable to related problems in biology or other scientific domains.
Création de la notice
27/02/2012 10:44
Dernière modification de la notice
03/03/2018 17:17
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