Inproceedings: An article in a conference proceedings.
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Zymosan induced arthritis in mice is biphasic and acts through the TLR2 pathway
Title of the conference
EULAR 2003, Annual European Congress of Rheumatology
Lisbon, Portugal, June 18-21, 2003
Annals of the Rheumatic Diseases
Zymosan induced arthritis is thought to be dependent on activation of the alternative pathway of complement and is short lived. Recently it has been demonstrated that zymosan is capable of activating the innate immune system via toll-like receptor 2 (TLR2) and TLR6. These receptors play a role in linking the innate to the adaptive immune response. We have therefore reinvestigated the mechanisms by which zymosan induces arthritis by analyzing the kinetic of inflammation, the joint histology, lymphocyte proliferation in wild type and TLR2 deficient mice.
Web of science
Last modification date