Coronary endothelial function assessment using self-gated cardiac cine MRI and k-t sparse SENSE.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_52A7E006FC12
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Coronary endothelial function assessment using self-gated cardiac cine MRI and k-t sparse SENSE.
Périodique
Magnetic resonance in medicine
Auteur(s)
Yerly J., Ginami G., Nordio G., Coristine A.J., Coppo S., Monney P., Stuber M.
ISSN
1522-2594 (Electronic)
ISSN-L
0740-3194
Statut éditorial
Publié
Date de publication
11/2016
Peer-reviewed
Oui
Volume
76
Numéro
5
Pages
1443-1454
Langue
anglais
Notes
Publication types: Evaluation Studies ; Journal Article
Publication Status: ppublish
Résumé
Electrocardiogram (ECG)-gated cine MRI, paired with isometric handgrip exercise, can be used to accurately, reproducibly, and noninvasively measure coronary endothelial function (CEF). Obtaining a reliable ECG signal at higher field strengths, however, can be challenging due to rapid gradient switching and an increased heart rate under stress. To address these limitations, we present a self-gated cardiac cine MRI framework for CEF measurements that operates without ECG signal.
Cross-sectional slices of the right coronary artery (RCA) were acquired using a two-dimensional golden angle radial trajectory. This sampling approach, combined with the k-t sparse SENSE algorithm, allows for the reconstruction of both real-time images for self-gating signal calculations and retrospectively reordered self-gated cine images. CEF measurements were quantitatively compared using both the self-gated and the standard ECG-gated approach.
Self-gated cine images with high-quality, temporal, and spatial resolution were reconstructed for 18 healthy volunteers. CEF as measured in self-gated images was in good agreement (R2  = 0.60) with that measured by its standard ECG-gated counterpart.
High spatial and temporal resolution cross-sectional cine images of the RCA can be obtained without ECG signal. The coronary vasomotor response to handgrip exercise compares favorably with that obtained with the standard ECG-gated method. Magn Reson Med 76:1443-1454, 2015. © 2015 International Society for Magnetic Resonance in Medicine.

Mots-clé
Adult, Algorithms, Cardiac-Gated Imaging Techniques/methods, Coronary Angiography/methods, Coronary Vessels/diagnostic imaging, Exercise Test/methods, Female, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Magnetic Resonance Angiography/methods, Magnetic Resonance Imaging, Cine/methods, Male, Reproducibility of Results, Sensitivity and Specificity, Signal Processing, Computer-Assisted, Young Adult, compressed sensing, coronary, endothelial function, golden angle, k-t sparse SENSE, self-gated cardiac cine
Pubmed
Web of science
Création de la notice
24/03/2016 17:53
Dernière modification de la notice
20/08/2019 15:08
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