Biochemical markers of fatal hypothermia.

Détails

ID Serval
serval:BIB_5283973157FE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Biochemical markers of fatal hypothermia.
Périodique
Forensic Science International
Auteur(s)
Palmiere C., Bardy D., Letovanec I., Mangin P., Augsburger M., Ventura F., Iglesias K., Werner D.
ISSN
1872-6283 (Electronic)
ISSN-L
0379-0738
Statut éditorial
Publié
Date de publication
01/2013
Peer-reviewed
Oui
Volume
226
Numéro
1-3
Pages
54-61
Langue
anglais
Notes
Publication types: JOURNAL ARTICLE
Résumé
The aim of this study was to investigate the usefulness of postmortem biochemical investigations in the diagnosis of fatal hypothermia. 10 cases of fatal hypothermia and 30 control cases were selected. A series of biochemical parameters, such as glucose, acetone, 3-beta-hydroxybutyrate, isopropyl alcohol, free fatty acids, adrenaline, growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, cortisol, calcium, magnesium, C-reactive protein, procalcitonin as well as markers of renal and cardiac functions were measured in blood, postmortem serum from femoral blood, urine, vitreous and pericardial fluid. The results suggested that deaths due to hypothermia, especially in free-ethanol cases, are characterized by increased ketone levels in blood and other biological fluids, increased adrenaline concentrations in urine, increased cortisol levels in postmortem serum from femoral blood and increased free cortisol values in urine. Increased or decreased levels of other biological parameters are either the result of terminal metabolic changes or the expression of preexisting diseases and may provide information to elucidate the death process on a case-by-case basis.
Mots-clé
Hypothermia, Postmortem biochemistry, Biochemical markers, Ketone bodies, Blood
Pubmed
Web of science
Création de la notice
12/02/2013 15:47
Dernière modification de la notice
18/09/2018 17:25
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