Pancytopénie, schizocytose et hémolyse: les pièges diagnostiques d'une pathologie fréquente se manifestant comme une pathologie rare et grave [Pancytopenia, haemolytic anaemia, schistocytes: a frequent pathology mimicking a rare and serious pathology].

Détails

ID Serval
serval:BIB_522933753E5F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Pancytopénie, schizocytose et hémolyse: les pièges diagnostiques d'une pathologie fréquente se manifestant comme une pathologie rare et grave [Pancytopenia, haemolytic anaemia, schistocytes: a frequent pathology mimicking a rare and serious pathology].
Périodique
Praxis
Auteur(s)
Monti M., Canellini G., Trueb L., Cairoli A., Lamy O.
ISSN
1661-8157 (Print)
ISSN-L
1661-8157
Statut éditorial
Publié
Date de publication
2005
Volume
94
Numéro
1-2
Pages
31-34
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Résumé
A 83 years old woman presents to our hospital with fatigue and dyspnea since 2 weeks, followed by a painless icterus. On laboratory we discover a pancytopenia with severe haemolytic anaemia, thrombopenia and schistocytosis. This association suggest a thrombotic microangiopathy. In the presence of macrocytes, hypersegmented neutrophils and a low reticulocytes count, a vitamin screening was performed witch leads to the discovery of a vitamin B12 and folic acid deficiency. After initiation of a vitamin therapy we observe a reticulocytic crisis and thereafter the normalisation of the haematological parameters.
Mots-clé
Aged, Aged, 80 and over, Anemia, Hemolytic/etiology, Anemia, Hemolytic/pathology, Diagnosis, Differential, Erythrocyte Count, Erythrocytes, Abnormal/pathology, Folic Acid Deficiency/blood, Folic Acid Deficiency/diagnosis, Humans, Male, Pancytopenia/etiology, Pancytopenia/pathology, Reticulocytes/pathology, Vitamin B 12 Deficiency/blood, Vitamin B 12 Deficiency/diagnosis
Pubmed
Création de la notice
25/01/2008 14:55
Dernière modification de la notice
03/03/2018 17:12
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