Short-term variation in air pollution and in average lung function among never-smokers. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA)

Détails

ID Serval
serval:BIB_51E734C17024
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Short-term variation in air pollution and in average lung function among never-smokers. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA)
Périodique
American Journal of Respiratory and Critical Care Medicine
Auteur(s)
Schindler  C., Kunzli  N., Bongard  J. P., Leuenberger  P., Karrer  W., Rapp  R., Monn  C., Ackermann-Liebrich  U.
ISSN
1073-449X (Print)
Statut éditorial
Publié
Date de publication
02/2001
Volume
163
Numéro
2
Pages
356-61
Notes
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't --- Old month value: Feb
Résumé
The present analysis was directed at investigating associations between short-term variations in air pollutant levels (NO2, total suspended particulates [TSP], O3) and cross-sectional lung function (FVC, FEV1, and forced expiratory flow at 25% to 75% of FVC [FEF25-75]) within a random sample of 3,912 adult never-smokers from eight areas of Switzerland (i.e., participants in the Swiss Study on Air Pollution and Lung Diseases in Adults [SAPALDIA] cross-sectional study, 1991). Within each local data set, the logarithms of FVC, FEV1, and FEF25-75 were regressed against the 24-h-means of NO2 and TSP and the 8-h mean of O3 (10:00 A.M. to 6:00 P.M.) on the examination day, with control for subjects' sex, age, height and weight, seasonal fluctuations and weekly cycles and meteorologic factors. On average, a 10-microg/m3 increment in the daily level of NO2, TSP, and O3 was associated with decrements in FEV1 of 0.67% (95% confidence interval [CI]: 0.13% to 1.21%), 0.46% (95% CI: 0.14% to 0.78%), and 0.51% (95% CI: 0.13% to 0.88%), respectively. Moreover, 10-microg/m3 increments in NO2 and TSP were associated with decrements in FVC of 0.73% (95% CI: 0.22% to 1.23%) and 0.36% (95% CI: 0.06% to 0.66%), respectively, and a 10-microg/m3 increment in O(3) was associated with a decrement in FEF25-75 of 1.04% (95% CI: 0.22% to 1.85%). Our results suggest that FVC, FEV1, and FEF25-75 vary with the daily level of NO2, TSP, and O3, but that these measures of lung function do not allow separation of the effects of particulates from those of NO2.
Mots-clé
Adolescent Adult Air Pollutants/*adverse effects/analysis Cross-Cultural Comparison Female Humans *Lung Volume Measurements Male Middle Aged Respiratory Hypersensitivity/epidemiology/*etiology Respiratory Tract Diseases/epidemiology/*etiology Switzerland Urbanization
Pubmed
Web of science
Création de la notice
25/01/2008 10:49
Dernière modification de la notice
03/03/2018 17:12
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