Secretory IgA in human serum.

Détails

ID Serval
serval:BIB_51C64414F181
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Secretory IgA in human serum.
Périodique
Journal of Immunology
Auteur(s)
Waldman R.H., Mach J.P., Stella M.M., Rowe D.S.
ISSN
0022-1767 (Print)
ISSN-L
0022-1767
Statut éditorial
Publié
Date de publication
1970
Volume
105
Numéro
1
Pages
43-47
Langue
anglais
Résumé
Secretory component (SC) was detected by the radioactive single radial diffusion technique in nearly all sera examined. The SC was shown to be associated with polymeric serum IgA. The mean level of secretory IgA (SIgA) in normal sera from India, Africa and Europe was about 0.03 to 0.04 mg/ml. The mean level was elevated in patients with a variety of disorders involving secretory surfaces (e.g., acute bacterial enterocolitis or respiratory tract carcinoma), but also in disorders with no known involvement of secretory surfaces. The highest levels were seen in lactating women, with a mean level five times higher than that in the general population. SIgA was also found at lower levels in cord serum, serum from breast-fed newborns and serum from children 3 to 10 years old.
Mots-clé
Africa, Antibodies/analysis, Antibody Specificity, Blood, Child, Child, Preschool, Cholera/immunology, Colostrum/immunology, Dermatitis/immunology, Dysentery/immunology, Enterocolitis, Pseudomembranous/immunology, Europe, Female, Fever/immunology, Humans, Immune Sera, Immunodiffusion, Immunoelectrophoresis, Immunoglobulin G/analysis, India, Infant, Infant, Newborn, Kidney Failure, Chronic/immunology, Lactation, Male, Multiple Myeloma/immunology, Osteomyelitis/immunology, Pregnancy, Respiratory Tract Neoplasms, Umbilical Cord
Pubmed
Web of science
Création de la notice
24/04/2013 10:33
Dernière modification de la notice
03/03/2018 17:11
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