PET-CT Principles and clinical applications

Details

Serval ID
serval:BIB_517FA40DEEB4
Type
A part of a book
Collection
Publications
Institution
Title
PET-CT Principles and clinical applications
Title of the book
Husband & Reznek's Imaging in Oncology
Author(s)
SCHAEFER Niklaus
Publisher
CRC Press
ISBN
9780203732656
Publication state
Published
Issued date
18/10/2020
Editor
Sahdev Anju, Vinnicombe Sarah J.
Series
Niklaus SCHAEFER
Language
english
Abstract
Positron-emission tomography (PET) is an important tool in cancer diagnostics since it allows virtually any biochemical process in the human body to be followed with positron-emitting radiotracers, injected in picomolar quantities (1). Radiotracers consist of a radioactive, positron-emitting isotope, linked to a biological tracer, targeting any biochemical process, receptor or any other druggable target (2). Isotopes suitable for PET imaging are proton-rich, such as 18F, 13N, 15O, 68Ga, 82Rb, or 89Zr and decay by emission of a neutron, a positron, and a neutrino. The emitted positron annihilates with a local electron after a short travel through matter (18F; ∼1 mm) with emission of two 511 keV gamma photons at 180° to each other.
Create date
22/06/2023 13:12
Last modification date
18/08/2023 6:56
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