Time of injection determines the effect of alpha-MSH antiserum on DA neurons in psychological stress

Détails

ID Serval
serval:BIB_510C5F6E951D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Time of injection determines the effect of alpha-MSH antiserum on DA neurons in psychological stress
Périodique
Peptides
Auteur(s)
Monnet F., Lichtensteiger W.
ISSN
0196-9781
Statut éditorial
Publié
Date de publication
1981
Peer-reviewed
Oui
Volume
2
Numéro
2
Pages
227-229
Langue
anglais
Résumé
Male rats were subjected to "psychological stress" which consisted in 10 sec footshock on the first day followed 24 hr later by a 10 sec stay in the experimental chamber without shock. Intravenous antiserum against alpha-MSH markedly changed the functional state of mesencephalic and hypothalamic DA neurons (assessed by histochemical microfluorimetry) when administered before the second session but not when given before the first session. These observations reveal an interesting parallelism in the temporal characteristics of the effects of alpha-MSH on avoidance behavior and central DA systems.
Mots-clé
Animals Brain/*physiopathology Dopamine/*physiology Humans Hypothalamus/physiopathology *Immune Sera Male Medulla Oblongata/physiopathology Melanocyte-Stimulating Hormones/*immunology Mesencephalon/physiopathology Microscopy, Fluorescence Neurons/*physiology Rats Stress, Psychological/*physiopathology Substantia Nigra/physiopathology
Pubmed
Web of science
Création de la notice
10/02/2009 14:05
Dernière modification de la notice
03/03/2018 17:10
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