Epidemiology of uveitis in children over a 10-year period.

Détails

ID Serval
serval:BIB_510B94EC4F08
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Epidemiology of uveitis in children over a 10-year period.
Périodique
Clinical and Experimental Rheumatology
Auteur(s)
Clarke L.A., Guex-Crosier Y., Hofer M.
ISSN
0392-856X (Print)
ISSN-L
0392-856X
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
31
Numéro
4
Pages
633-637
Langue
anglais
Notes
Publication types: JOURNAL ARTICLE
Résumé
OBJECTIVES: The aim of the present study is to investigate the demographics, aetiologies, complications, treatments and visual outcomes in paediatric uveitis patients in the French-speaking part of Switzerland. METHODS: Chart review of all patients diagnosed with uveitis before the age of 16 years, presenting to two tertiary referral centres (uveitis and paediatric rheumatology clinics) in Lausanne, Switzerland, between 2000 and 2009. RESULTS: Seventy-nine children (37 girls) were identified, 62 living in Switzerland, 15 in Europe and 2 in North Africa. Median age at first symptoms was 9.0 years (range 1.5-15.8 years), with a median follow-up time of 1.8 years (0-8 years). Both eyes were involved in 51 patients (64.6%). The course was acute in 30.4%, chronic in 60.8% and recurrent in 8.9%. Anterior uveitis occurred in 39.2%, intermediate in 32.9%, posterior in 22.8% and panuveitis in 5.1%. The three main diagnoses were idiopathic uveitis (34.2%), JIA-related uveitis (22.8%) and toxoplasmic retinochoroiditis (15.2%). During the last follow-up visit, the visual acuity (VA) was ≥8/10 in 72% of all eyes with a measurable VA. Cataract (8%), ocular hypertension/glaucoma (8%) and macular fibrosis (4%) were the three most common severe complications. Systemic steroids were given to 56% and biological agents to 24% of patients with inflammatory uveitis. CONCLUSIONS: Uveitis in children can be a devastating disease. A strict classification of aetiologies and a tight collaboration between paediatric rheumatologists and ophthalmologists are important to ensure early control of ocular inflammation and improve long-term visual prognosis.
Pubmed
Web of science
Création de la notice
04/03/2013 10:16
Dernière modification de la notice
19/03/2018 10:56
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