Carriage of methicillin-resistant Staphylococcus aureus at hospital admission.

Détails

ID Serval
serval:BIB_50AC83C7CD08
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Carriage of methicillin-resistant Staphylococcus aureus at hospital admission.
Périodique
Infection Control and Hospital Epidemiology
Auteur(s)
Troillet N., Carmeli Y., Samore M.H., Dakos J., Eichelberger K., DeGirolami P.C., Karchmer A.W.
ISSN
0899-823X (Print)
ISSN-L
0899-823X
Statut éditorial
Publié
Date de publication
1998
Peer-reviewed
Oui
Volume
19
Numéro
3
Pages
181-185
Langue
anglais
Notes
Publication types: Journal Article
Résumé
OBJECTIVES: To measure the prevalence of, and to establish predictors for, the nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) at hospital admission. To evaluate mannitol-salt agar with oxacillin for the simultaneous detection and identification of MRSA from nasal swabs.
DESIGN: Three-month prospective case-control survey, with data collected from interviews and computerized databases. The criterion standard for MRSA detection was culture on Mueller-Hinton agar with oxacillin 6 microg/mL (National Committee for Clinical Laboratory Standards method).
SETTING: 320-bed tertiary-care hospital.
PATIENTS: 387 patients screened within 24 hours after admission, including 10 MRSA carriers (cases), 291 patients with no S aureus, and 86 patients with methicillin-susceptible S aureus.
RESULTS: The prevalence of MRSA nasal carriage was 2.6%, whereas the prevalence of carriage was 3.1% when both nasal and wound cultures were performed. The significant predictors of carriage were a prior detection of MRSA, open wounds, diabetes mellitus, treatments by injection, prior nursing home stays, visits at home by a nurse, and prior antibiotic treatments. Cases had stayed for longer periods in hospitals and had received longer antibiotic treatments within a year. Eighty patients (including the 10 cases) had diabetes, had been exposed to healthcare facilities within a year, and had antibiotics within 6 months. The sensitivity and negative predictive value of nasal swabs on mannitol-salt agar with oxacillin were 60% and 71%, respectively.
CONCLUSION: MRSA carriage on admission to the hospital may be an increasing and underestimated problem. Further studies are needed to develop and validate a sensitive and specific prediction rule.
Mots-clé
Adolescent, Adult, Aged, Aged, 80 and over, Carrier State/epidemiology, Carrier State/microbiology, Case-Control Studies, Female, Humans, Male, Methicillin Resistance, Middle Aged, Patient Admission, Prevalence, Prospective Studies, Staphylococcal Infections/epidemiology, Switzerland
Pubmed
Création de la notice
28/12/2013 18:50
Dernière modification de la notice
03/03/2018 17:09
Données d'usage