Why the move to microfluidics for protein analysis?

Details

Serval ID
serval:BIB_4FC628382D3F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Why the move to microfluidics for protein analysis?
Journal
Current Opinion in Biotechnology
Author(s)
Lion N., Reymond F., Girault H.H., Rossier J.S.
ISSN
0958-1669 (Print)
ISSN-L
0958-1669
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
15
Number
1
Pages
31-37
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review Publication Status: ppublish
Abstract
There has been a recent trend towards the miniaturization of analytical tools, but what are the advantages of microfluidic devices and when is their use appropriate? Recent advances in the field of micro-analytical systems can be classified according to instrument performance (which refers here to the desired property of the analytical tool of interest) and two important features specifically related to miniaturisation, namely reduction of the sample volume and the time-to-result. Here we discuss the contribution of these different parameters and aim to highlight the factors of choice in the development and use of microfluidic devices dedicated to protein analysis.
Keywords
Animals, Chromatography/instrumentation, Chromatography/methods, Electrophoresis/instrumentation, Electrophoresis/methods, Equipment Design, Flow Injection Analysis/instrumentation, Flow Injection Analysis/methods, Humans, Microchemistry/instrumentation, Microchemistry/methods, Microfluidics/instrumentation, Microfluidics/methods, Miniaturization/methods, Proteins/analysis, Proteins/chemistry, Specimen Handling/instrumentation, Specimen Handling/methods, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/instrumentation, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, Technology Assessment, Biomedical
Pubmed
Web of science
Create date
09/11/2014 23:50
Last modification date
20/08/2019 15:05
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