Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Langerhans' cell histiocytosis and the nervous system.
Journal of Neurology
Publication types: Case Reports ; Journal Article ; ReviewPublication Status: ppublish
We report two cases of Langerhans' cell histiocytosis with unusual central nervous system (CNS) involvement. The first patient had behavioural disturbances, memory loss and diabetes insipidus. His response to a range of treatments was poor. The second patient presented with seizures and headaches suggestive of raised intracranial pressure. Etoposide (VP16) chemotherapy led to a dramatic clinical and radiological improvement. The various CNS manifestations of Langerhans' cell histiocytosis and their management are discussed.
Adult, Central Nervous System Diseases/etiology, Central Nervous System Diseases/radiography, Histiocytosis, Langerhans-Cell/complications, Histiocytosis, Langerhans-Cell/diagnosis, Humans, Male, Tomography, X-Ray Computed
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