Genome-wide expression patterns and the genetic architecture of a fundamental social trait.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_4EA4893DF81F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Genome-wide expression patterns and the genetic architecture of a fundamental social trait.
Périodique
PLoS Genetics
Auteur(s)
Wang J., Ross K.G., Keller L.
ISSN
1553-7404
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
4
Numéro
7
Pages
e1000127
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Résumé
Explaining how interactions between genes and the environment influence social behavior is a fundamental research goal, yet there is limited relevant information for species exhibiting natural variation in social organization. The fire ant Solenopsis invicta is characterized by a remarkable form of social polymorphism, with the presence of one or several queens per colony and the expression of other phenotypic and behavioral differences being completely associated with allelic variation at a single Mendelian factor marked by the gene Gp-9. Microarray analyses of adult workers revealed that differences in the Gp-9 genotype are associated with the differential expression of an unexpectedly small number of genes, many of which have predicted functions, implying a role in chemical communication relevant to the regulation of colony queen number. Even more surprisingly, worker gene expression profiles are more strongly influenced by indirect effects associated with the Gp-9 genotypic composition within their colony than by the direct effect of their own Gp-9 genotype. This constitutes an unusual example of an "extended phenotype" and suggests a complex genetic architecture with a single Mendelian factor, directly and indirectly influencing the individual behaviors that, in aggregate, produce an emergent colony-level phenotype.
Mots-clé
Alleles, Animals, Ants, Gene Expression Profiling, Gene Expression Regulation, Genes, Insect, Genetic Variation, Genotype, Haplotypes, Heterozygote, Homozygote, Insect Proteins, Oligonucleotide Array Sequence Analysis, Social Behavior
Pubmed
Web of science
Open Access
Oui
Création de la notice
10/06/2008 20:19
Dernière modification de la notice
20/08/2019 14:04
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