Self-management is a process in which the patient actively engages in the management of his or her disease, adapting to the resulting problems, and complying with behavioral changes. Its support will have beneficial effects, as well as an improvement in quality of life, and reasonable use of resources available for health. Exercise plays a central role in the self-management of a range of chronic diseases, including musculoskeletal conditions, one of the most prevalent conditions in Switzerland. However, physical activity and exercise are under-prescribed in chronic disease management. A combination of supervised strategies and digital devices in self-management coaching could maximize the effects of physical activity.