Bilateral sequential optic neuropathy as the initial manifestation of Sjögren syndrome.

Détails

ID Serval
serval:BIB_4CC6F6EFC0F6
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Bilateral sequential optic neuropathy as the initial manifestation of Sjögren syndrome.
Périodique
Klinische Monatsblätter für Augenheilkunde
Auteur(s)
Pournaras J.A., Vaudaux J.D., Borruat F.X.
ISSN
0023-2165 (Print)
ISSN-L
0023-2165
Statut éditorial
Publié
Date de publication
04/2007
Peer-reviewed
Oui
Volume
224
Numéro
4
Pages
337-339
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
BACKGROUND: Neuro-ophthalmic findings are uncommon in the setting of Sjögren syndrome. We report the case of a patient with bilateral, sequential optic neuropathy as the initial manifestation of Sjögren syndrome.
HISTORY AND SIGNS: A 38-year-old male presented with sudden painless visual loss in his left eye in May 2005. Fundus examination revealed a left swollen optic disk. Magnetic resonance imaging (MRI) revealed a left optic nerve lesion. Elevated titres of autoantibodies (ANA, anti-SSA, anti-SSB) were found, suggestive of Sjögren syndrome. In January 2006, he presented with painful sudden visual loss in the right eye. Fundus examination revealed a right swollen optic disk and left optic nerve atrophy. MRI was normal. Other aetiologies were ruled out.
THERAPY AND OUTCOME: Each episode was treated with intravenous methylprednisolone (1 g/day during 3 days), followed by oral prednisone (1 mg/kg/day). Moderate improvement of vision ensued in both eyes.
CONCLUSIONS: Atypical presentation of an optic neuropathy must raise the suspicion of an unusual aetiology. Our case illustrates how a bilateral sequential optic neuropathy in an otherwise healthy patient can result from an unusual inflammatory aetiology: primary Sjögren syndrome.
Mots-clé
Adult, Anti-Inflammatory Agents/administration & dosage, Drug Combinations, Humans, Male, Methylprednisolone/administration & dosage, Optic Nerve Diseases/diagnosis, Optic Nerve Diseases/drug therapy, Prednisone/administration & dosage, Sjogren's Syndrome/complications, Sjogren's Syndrome/diagnosis, Treatment Outcome
Pubmed
Web of science
Création de la notice
28/01/2008 12:37
Dernière modification de la notice
20/08/2019 14:01
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