Hepatitis C: an update.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_4B2C50C88F58
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hepatitis C: an update.
Journal
Swiss medical weekly
Author(s)
Moradpour D., Cerny A., Heim M.H., Blum H.E.
ISSN
1424-7860 (Print)
ISSN-L
0036-7672
Publication state
Published
Issued date
02/06/2001
Peer-reviewed
Oui
Volume
131
Number
21-22
Pages
291-298
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. While current therapeutic options for hepatitis C are limited, recent progress in the understanding of the biology of HCV led to the identification of novel targets for antiviral intervention. In addition, molecular and immunotherapeutic strategies to inhibit HCV replication or gene expression and to enhance the cellular immune response against HCV are being explored. These and other novel antiviral strategies may eventually complement existing therapeutic modalities. Here, we briefly review current concepts of the epidemiology, molecular virology, pathogenesis, natural history, diagnosis, therapy, and prevention of hepatitis C.

Keywords
Antiviral Agents/therapeutic use, Enzyme-Linked Immunosorbent Assay, Hepacivirus/isolation & purification, Hepatitis C/diagnosis, Hepatitis C/epidemiology, Hepatitis C/therapy, Humans, Reverse Transcriptase Polymerase Chain Reaction
Pubmed
Web of science
Create date
25/01/2008 16:05
Last modification date
20/08/2019 13:59
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