Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.

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Serval ID
serval:BIB_4B100A96DC0B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.
Journal
Clinical Pharmacology and Therapeutics
Author(s)
Iyer L., Hall D., Das S., Mortell M.A., Ramírez J., Kim S., Di Rienzo A., Ratain M.J.
ISSN
0009-9236 (Print)
ISSN-L
0009-9236
Publication state
Published
Issued date
1999
Volume
65
Number
5
Pages
576-582
Language
english
Keywords
Antineoplastic Agents, Phytogenic/metabolism, Bilirubin/metabolism, Camptothecin/analogs & derivatives, Camptothecin/metabolism, Genotype, Glucuronosyltransferase/genetics, Humans, Liver/enzymology, Liver/metabolism, Phenotype, Polymorphism, Genetic, Promoter Regions, Genetic/genetics
DOI
10.1016/S0009-9236(99)70078-0
Pubmed
10340924
Create date
27/02/2012 17:58
Last modification date
20/08/2019 14:58
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