Influence of the excitation wavelength on the tumor-to-healthy contrast in autofluorescence bronchoscopy: a comprehensive study

Details

Serval ID
serval:BIB_4A64BB7F8B17
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Influence of the excitation wavelength on the tumor-to-healthy contrast in autofluorescence bronchoscopy: a comprehensive study
Journal
Proceedings SPIE
Author(s)
Gabrecht T., Uehlinger P., Andrejevic Blant S., Grosjean P., Radu A., Monnier Ph., Weber B. C., van den Bergh H., Wagnières G.
ISSN
1996-756X
Publication state
Published
Issued date
2005
Volume
5862
Pages
586207
Language
english
Notes
Conference Title: Diagnostic Optical Spectroscopy in Biomedicine III Optical Spectroscopy: In vivo Human Studies
Abstract
Autofluorescence (AF) bronchoscopy is a useful tool for early cancer detection. However the mechanisms involved in this diagnosis procedure are poorly understood. We present an in vivo autofluorescence imaging study to access the depth of the principal contrast mechanisms within the bronchial tissue comparing a narrow band and broad band violet fluorescence excitation. Knowledge of this parameter is crucial for the optimization of the spectral and optical design of clinical diagnostic AF imaging devices. We observed no differences in the chromatic contrast using the two excitation modes, indicating that the principal contrast mechanisms have a non-superficial character.
Create date
16/12/2008 9:41
Last modification date
20/08/2019 13:58
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