Tissue Specificity and Dynamics of Sex-Biased Gene Expression in a Common Frog Population with Differentiated, Yet Homomorphic, Sex Chromosomes.

Détails

Ressource 1Télécharger: genes-09-00294.pdf (3902.27 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_498DF6625836
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Tissue Specificity and Dynamics of Sex-Biased Gene Expression in a Common Frog Population with Differentiated, Yet Homomorphic, Sex Chromosomes.
Périodique
Genes
Auteur(s)
Ma W.J., Veltsos P., Toups M.A., Rodrigues N., Sermier R., Jeffries D.L., Perrin N.
ISSN
2073-4425 (Print)
ISSN-L
2073-4425
Statut éditorial
Publié
Date de publication
2018
Peer-reviewed
Oui
Volume
9
Numéro
6
Pages
294
Langue
anglais
Résumé
Sex-biased genes are central to the study of sexual selection, sexual antagonism, and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome in the common frog <i>Rana temporaria</i> based on five developmental stages and three adult tissues from both sexes, obtained from a population with karyotypically homomorphic but genetically differentiated sex chromosomes. This allows the study of sex-biased gene expression throughout development, and its effect on the rate of gene evolution while accounting for pleiotropic expression, which is known to negatively correlate with the evolutionary rate. Overall, sex-biased genes had little overlap among developmental stages and adult tissues. Late developmental stages and gonad tissues had the highest numbers of stage- or tissue-specific genes. We find that pleiotropic gene expression is a better predictor than sex bias for the evolutionary rate of genes, though it often interacts with sex bias. Although genetically differentiated, the sex chromosomes were not enriched in sex-biased genes, possibly due to a very recent arrest of XY recombination. These results extend our understanding of the developmental dynamics, tissue specificity, and genomic localization of sex-biased genes.
Mots-clé
adult tissues, development, gene expression, pleiotropy, rate of evolution, sex bias, sex chromosomes, tissue specificity
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/06/2018 8:56
Dernière modification de la notice
20/08/2019 13:56
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