Thrombozytenhemmung und -aktivierung Mechanismen und klinische Implikationen [Platelet inhibition and activation. Mechanisms and clinical implications].
Details
Serval ID
serval:BIB_48F499EBC476
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Thrombozytenhemmung und -aktivierung Mechanismen und klinische Implikationen [Platelet inhibition and activation. Mechanisms and clinical implications].
Journal
Herz
ISSN
1615-6692 (Electronic)
ISSN-L
0340-9937
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
30
Number
3
Pages
176-180
Language
german
Notes
Publication types: English Abstract ; Journal Article ; Review Publication Status: ppublish
Abstract
The sensitivity to activation of platelets is part of the delicate equilibrium differentiating hemostasis from thrombosis. Under physiological conditions it is maintained by downregulating platelet activity and removing agonists. Under pathologic conditions the clinician tries to restore this equilibrium with pharmaceutical drugs. The results obtained by such treatments are steadily improving but there is still need for better knowledge of the mechanisms involved and for alternative inhibitors.
Keywords
Animals, Blood Platelets/drug effects, Blood Platelets/immunology, Humans, Models, Immunological, Platelet Activation/drug effects, Platelet Activation/immunology, Platelet Aggregation Inhibitors/administration & dosage, Thrombosis/physiopathology, Thrombosis/prevention & control
Pubmed
Web of science
Create date
10/02/2015 12:15
Last modification date
20/08/2019 14:56
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