Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Thrombozytenhemmung und -aktivierung Mechanismen und klinische Implikationen [Platelet inhibition and activation. Mechanisms and clinical implications].
Publication types: English Abstract ; Journal Article ; Review Publication Status: ppublish
The sensitivity to activation of platelets is part of the delicate equilibrium differentiating hemostasis from thrombosis. Under physiological conditions it is maintained by downregulating platelet activity and removing agonists. Under pathologic conditions the clinician tries to restore this equilibrium with pharmaceutical drugs. The results obtained by such treatments are steadily improving but there is still need for better knowledge of the mechanisms involved and for alternative inhibitors.
Animals, Blood Platelets/drug effects, Blood Platelets/immunology, Humans, Models, Immunological, Platelet Activation/drug effects, Platelet Activation/immunology, Platelet Aggregation Inhibitors/administration & dosage, Thrombosis/physiopathology, Thrombosis/prevention & control
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