Immunotherapy for gynaecological malignancies.

Détails

ID Serval
serval:BIB_47B040083A01
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Immunotherapy for gynaecological malignancies.
Périodique
Expert Opinion On Biological Therapy
Auteur(s)
Coukos G., Conejo-Garcia J.R., Roden R.B., Wu T.C.
ISSN
1744-7682 (Electronic)
ISSN-L
1471-2598
Statut éditorial
Publié
Date de publication
2005
Volume
5
Numéro
9
Pages
1193-1210
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; ReviewPublication Status: ppublish
Résumé
Gynaecological malignancies, excluding breast cancer, cause approximately 25,000 deaths yearly among women in the US. Therefore, novel approaches for the prevention or treatment of these diseases are urgently required. In the case of cervical cancer, human papillomavirus (HPV) xenoantigens are readily recognised by the immune system, and their targeting has shown great promise in preclinical models of therapeutic vaccination and in clinical studies of preventative vaccination. A growing body of evidence indicates that ovarian cancer is also immunogenic and can thus be targeted through immunotherapy. This review outlines the principles and problems of immunotherapy for cervical and ovarian cancer, including the authors' personal assessment.
Mots-clé
Adoptive Transfer, Animals, Antigens, Heterophile/immunology, Antigens, Neoplasm/immunology, Cancer Vaccines/therapeutic use, Clinical Trials as Topic, Cytokines, Drug Evaluation, Preclinical, Female, Genital Neoplasms, Female/immunology, Genital Neoplasms, Female/prevention & control, Humans, Immunotherapy/methods, Lymphocytes, Tumor-Infiltrating/immunology, Lymphocytes, Tumor-Infiltrating/transplantation, Ovarian Neoplasms/immunology, Ovarian Neoplasms/prevention & control, Papillomaviridae/immunology, T-Lymphocytes, Regulatory, Uterine Cervical Neoplasms/immunology, Uterine Cervical Neoplasms/prevention & control, Vaccines, Attenuated/therapeutic use, Viral Vaccines/therapeutic use
Pubmed
Création de la notice
14/10/2014 12:43
Dernière modification de la notice
03/03/2018 16:50
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