Experimental bacterial endocarditis after dental extractions in rats with periodontitis.

Détails

ID Serval
serval:BIB_46F405BB0C65
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Experimental bacterial endocarditis after dental extractions in rats with periodontitis.
Périodique
Journal of Infectious Diseases
Auteur(s)
Overholser C.D., Moreillon P., Glauser M.P.
ISSN
0022-1899 (Print)
ISSN-L
0022-1899
Statut éditorial
Publié
Date de publication
1987
Volume
155
Numéro
1
Pages
107-112
Langue
anglais
Résumé
The development of bacterial endocarditis was analyzed after dental extractions in rats with or without periodontal disease. Periodontal disease was produced in rats by tying silk ligatures around the two maxillary first molars and placing the animals on a high sucrose diet for 14 weeks. Sterile aortic valve vegetations were produced by means of a transaortic catheter, and 24 hr later the maxillary first molars were extracted. The animals were killed 72 hr after the extractions. In rats with periodontal disease, extractions resulted in a 48% (14 of 29) incidence of bacterial endocarditis, most cases of which were due to Streptococcus spp. (one was caused by Staphylococcus aureus). In contrast, when the teeth with a healthy periodontium were extracted, only 6% (one of 15) of the rats developed endocarditis. When catheters were placed in animals with periodontal disease but no extractions were performed, no endocarditis occurred.
Mots-clé
Animals, Aortic Valve, Disease Models, Animal, Endocarditis, Bacterial/etiology, Female, Heart Catheterization, Periodontitis/complications, Rats, Rats, Inbred Strains, Staphylococcal Infections/etiology, Streptococcal Infections/etiology, Tooth Extraction/adverse effects
Pubmed
Création de la notice
24/01/2008 14:58
Dernière modification de la notice
03/03/2018 16:48
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