Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

Details

Serval ID
serval:BIB_46D70ED0BAEC
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction
Journal
Immunity
Author(s)
Muppidi  J. R., Tschopp  J., Siegel  R. M.
ISSN
1074-7613 (Print)
Publication state
Published
Issued date
10/2004
Volume
21
Number
4
Pages
461-5
Notes
Journal Article
Review --- Old month value: Oct
Abstract
Signaling by receptors in the TNF receptor (TNFR) superfamily mediate biological outcomes ranging from inflammation to apoptosis and other forms of programmed cell death. How receptor signaling mediates these divergent responses is just beginning to be understood. Here, we discuss how receptor submembrane localization and the formation of alternate signaling complexes can alter the fate of cells stimulated through TNFRs with a death domain, also known as "death receptors."
Keywords
Animals Cell Death/*physiology Humans Membrane Microdomains/*physiology Receptors, Tumor Necrosis Factor/*physiology Signal Transduction/*physiology
Pubmed
Web of science
Open Access
Yes
Create date
24/01/2008 16:19
Last modification date
20/08/2019 14:52
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