Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging.

Détails

ID Serval
serval:BIB_458B5F37378B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging.
Périodique
Magnetic Resonance in Medicine
Auteur(s)
Wedeen V.J., Hagmann P., Tseng W.Y., Reese T.G., Weisskoff R.M.
ISSN
0740-3194 (Print)
ISSN-L
0740-3194
Statut éditorial
Publié
Date de publication
2005
Volume
54
Numéro
6
Pages
1377-1386
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Methods are presented to map complex fiber architectures in tissues by imaging the 3D spectra of tissue water diffusion with MR. First, theoretical considerations show why and under what conditions diffusion contrast is positive. Using this result, spin displacement spectra that are conventionally phase-encoded can be accurately reconstructed by a Fourier transform of the measured signal's modulus. Second, studies of in vitro and in vivo samples demonstrate correspondence between the orientational maxima of the diffusion spectrum and those of the fiber orientation density at each location. In specimens with complex muscular tissue, such as the tongue, diffusion spectrum images show characteristic local heterogeneities of fiber architectures, including angular dispersion and intersection. Cerebral diffusion spectra acquired in normal human subjects resolve known white matter tracts and tract intersections. Finally, the relation between the presented model-free imaging technique and other available diffusion MRI schemes is discussed.
Mots-clé
Algorithms, Animals, Brain/cytology, Cattle, Diffusion Magnetic Resonance Imaging/methods, Fourier Analysis, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Imaging, Three-Dimensional/methods, Muscle Fibers, Skeletal/cytology, Muscle, Skeletal/cytology, Nerve Fibers, Myelinated/ultrastructure, Reproducibility of Results, Sensitivity and Specificity, Spectrum Analysis/methods
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/06/2012 9:03
Dernière modification de la notice
08/05/2019 17:54
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