Intoxication massive au cyanure avec evolution favorable. Etude hemodynamique. [Massive poisoning with cyanide with favorable outcome. Hemodynamic study]

Détails

ID Serval
serval:BIB_45609B307D64
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Intoxication massive au cyanure avec evolution favorable. Etude hemodynamique. [Massive poisoning with cyanide with favorable outcome. Hemodynamic study]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur(s)
Feihl  F., Domenighetti  G., Perret  C.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
09/1982
Volume
112
Numéro
37
Pages
1280-2
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Sep 11
Résumé
A 60-year-old chemist was admitted two hours after voluntary intake of 600 mg KCL. Upon admission he was in deep coma and bradypneic but non-cyanotic. Arterial blood gas analysis showed severe lactic acidosis; blood cyanide concentration was well above the lethal level. The patient was intubated and artificially ventilated with highly hyperoxic mixtures. Specific treatment included sodium nitrite and sodium thiosulfate. The patient recovered without sequelae despite excessive methemoglobinemia. The hemodynamic study upon admission showed a hyperdynamic status associated with low peripheral resistances and normal filling pressures, a profile similar to that described in response to acute anoxia in experimental animals.
Mots-clé
Cyanides/*poisoning Dose-Response Relationship, Drug Hemodynamic Processes/*drug effects Humans Lactates/blood Male Middle Aged Potassium Cyanide/*poisoning Suicide, Attempted
Pubmed
Web of science
Création de la notice
25/01/2008 10:37
Dernière modification de la notice
03/03/2018 16:45
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