Progressive decline of decision-making performances during multiple sclerosis.

Détails

ID Serval
serval:BIB_454F8ACC0454
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Progressive decline of decision-making performances during multiple sclerosis.
Périodique
Journal of the International Neuropsychological Society
Auteur(s)
Simioni S., Ruffieux C., Kleeberg J., Bruggimann L., du Pasquier R.A., Annoni J.M., Schluep M.
ISSN
1469-7661[electronic]
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
15
Numéro
2
Pages
291-295
Langue
anglais
Résumé
The purpose of this study was to evaluate longitudinally, using the Iowa Gambling Task (IGT), the dynamics of decision-making capacity at a two-year interval (median: 2.1 years) in a group of patients with multiple sclerosis (MS) (n = 70) and minor neurological disability [Expanded Disability Status Scale (EDSS) < or = 2.5 at baseline]. Cognition (memory, executive functions, attention), behavior, handicap, and perceived health status were also investigated. Standardized change scores [(score at retest-score at baseline)/standard deviation of baseline score] were computed. Results showed that IGT performances decreased from baseline to retest (from 0.3, SD = 0.4 to 0.1, SD = 0.3, p = .005). MS patients who worsened in the IGT were more likely to show a decreased perceived health status and emotional well-being (SEP-59; p = .05 for both). Relapsing rate, disability progression, cognitive, and behavioral changes were not associated with decreased IGT performances. In conclusion, decline in decision making can appear as an isolated deficit in MS.
Mots-clé
Adult, Decision Making, Disability Evaluation, Disease Progression, Female, Humans, Longitudinal Studies, Male, Middle Aged, Multiple Sclerosis, Neuropsychological Tests, Young Adult
Pubmed
Web of science
Création de la notice
29/05/2009 14:34
Dernière modification de la notice
03/03/2018 16:45
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