Radiofrequency Ablation of Liver Tumors: No Difference in the Ablation Zone Volume Between Cirrhotic and Healthy Liver.

Détails

ID Serval
serval:BIB_4545C463B2EA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Radiofrequency Ablation of Liver Tumors: No Difference in the Ablation Zone Volume Between Cirrhotic and Healthy Liver.
Périodique
Cardiovascular and interventional radiology
Auteur(s)
Cassinotto C., Denys A., Gay F., Duran R., Hocquelet A., Piron L., Guiu B.
ISSN
1432-086X (Electronic)
ISSN-L
0174-1551
Statut éditorial
Publié
Date de publication
06/2018
Peer-reviewed
Oui
Volume
41
Numéro
6
Pages
905-911
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The "oven effect" theory assumes that radiofrequency ablation (RFA) would be more efficient on tumors of cirrhotic livers. The aim of the study was to compare the size and volume of the ablation zone following RFA on tumors of cirrhotic versus healthy livers.
One hundred and eleven patients who underwent RFA from 2011 to 2013 for the treatment of 140 liver tumors (83 hepatocellular carcinomas developed on a cirrhotic liver, i.e., "cirrhosis group," and 57 tumors developed on a healthy liver, mainly liver metastasis, i.e., "healthy liver group") using the same RFA device were retrospectively selected. The diameter and volume of the ablation zone were compared between groups at the end of the procedure (FU0), at first (FU1) and second follow-up (FU2) performed 1.6 months (± 19 days) and 4.7 months (± 40 days) post-RFA, respectively.
No differences in the size or volume of the ablation zone were found between groups at FU0 (36.5 ± 12 mm vs. 34.3 ± 10 mm, p = 0.5; and 28 ± 16 mm <sup>3</sup> vs. 26.5 ± 16 mm <sup>3</sup> , p = 0.6, respectively), FU1, or FU2. Similarly, no differences were found at FU0, FU1, or FU2 in the subgroups of tumors treated using a single radiofrequency application. The mean volume of the ablation zone decreased over time, by 33.3% at FU1 and 48.5% at FU2, without any difference between groups.
In contradiction to the "oven effect" theory, RFA achieves ablation zones of a comparable size and volume in cirrhotic and healthy livers.
Mots-clé
Carcinoma, Hepatocellular/complications, Carcinoma, Hepatocellular/diagnostic imaging, Carcinoma, Hepatocellular/surgery, Catheter Ablation/methods, Female, Humans, Liver/diagnostic imaging, Liver/surgery, Liver Cirrhosis/complications, Liver Cirrhosis/diagnostic imaging, Liver Cirrhosis/surgery, Liver Neoplasms/complications, Liver Neoplasms/diagnostic imaging, Liver Neoplasms/surgery, Magnetic Resonance Imaging, Male, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome, Hepatocellular carcinoma, Interventional radiology, Liver metastasis, Liver neoplasms, Percutaneous radiofrequency ablation
Pubmed
Web of science
Création de la notice
01/03/2018 17:55
Dernière modification de la notice
20/08/2019 14:50
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