Running related injury is a complex, multifactorial phenomenon that remains difficult to explain. However, there are available tools for clinicians allowing prevention (primary or tertiary) and rehabilitation optimization, thus reducing the consequences of the injury and time before returning to participation. These tools rely mainly on training load monitoring and clinical evaluation of stride biomechanical analysis. Unfortunately, they currently remain poorly known by practitioners, while allowing the opportunity to address the challenge of managing the injured runner, including a faster return to run, but also the prevention of a potential recurrence. It requires targeted intervention and education of the patient on the factors leading to the injury.