Determinants of Pesticide Exposure in Occupational Studies: A Meta-Analysis.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_449C90B2AD24
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Determinants of Pesticide Exposure in Occupational Studies: A Meta-Analysis.
Journal
Toxics
Author(s)
Oltramare C., Mediouni Z., Shoman Y., Hopf N.B., Graczyk H., Berthet A.
ISSN
2305-6304 (Electronic)
ISSN-L
2305-6304
Publication state
Published
Issued date
18/07/2023
Peer-reviewed
Oui
Volume
11
Number
7
Pages
623
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
Few epidemiological studies use exposure determinants specifically tailored to assess pesticide or plant protection product (PPP) exposures when assessing presumed association between occupational exposure and health outcomes among agricultural workers. This lack of exposure specificity could lead to results that fail to detect an association. It could be related to the lack of consensus on exposure assessment methods and the choice of exposure determinants. We conducted a meta-analysis following the PRISMA checklist to identify PPP exposure determinants used in occupational studies and identified exposure determinants that best characterized agricultural exposures to PPPs. Out of 1436 studies identified, 71 were included. The exposure determinants identified were active ingredients, chemical classes, types of PPP, crops, tasks, frequencies, duration, lifetime exposure days, and intensity-weighted exposure days. Only six over 17 associations between exposure determinants and health outcomes were found with moderate quality of evidence. Overall, epidemiological studies had difficulty defining relevant determinants to characterize PPP exposures for agricultural workers. We recommend that a standardized list of determinants for PPP exposures in occupational exposure studies should include information on formulations, intensity, duration, and frequency of PPP exposure. Harmonized data collection on exposure and health outcomes are required as well as standard units for each exposure determinant.
Keywords
Chemical Health and Safety, Health, Toxicology and Mutagenesis, Toxicology, determinant of exposure, occupational exposure, pesticides
Pubmed
Web of science
Open Access
Yes
Create date
20/07/2023 12:20
Last modification date
05/10/2023 6:58
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