Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Neuropathie optique rétrobulbaire post-actinique [Post-actinic retrobulbar optic neuropathy]
Klinische Monatsblätter für Augenheilkunde
Publication types: Case Reports ; English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
BACKGROUND: Radiation optic neuropathy (RON) is a rare, unpredictable, late complication of radiotherapy secondary to obliterative endarteritis. Tumor recurrence has to be ruled out by a clinical and neuroradiological examination. METHODS: Five patients with RON were investigated by magnetic resonance imaging (MRI) during 1992. RESULTS: Radiation-induced lesions of the intracranial visual pathways were easily visible on MRI. Without Gadolinium, a sectorial swelling was detectable, which markedly enhanced with Gadolinium. Intracranial optic nerve was affected in 5/5 cases, optic chiasm in 3/5 cases, and optic tract in 2/5 cases. CONCLUSIONS: MRI is the examination of choice when RON is suspected: it will easily delineate the extent of the lesion, and compression/infiltration by a recurrent tumor will be formally ruled out. A segmental swelling of visual pathway with marked Gadolinium enhancement on MRI is highly suggestive of radionecrosis.
Cranial Irradiation, Female, Head and Neck Neoplasms, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Optic Nerve, Optic Neuritis, Radiation Injuries, Radiotherapy Dosage, Visual Acuity, Visual Fields
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