The clinical implication of lymph nodes micrometastases and isolated tumor cells in patients with cervical cancer: A systematic review.

Details

Serval ID
serval:BIB_441EDF72434F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The clinical implication of lymph nodes micrometastases and isolated tumor cells in patients with cervical cancer: A systematic review.
Journal
European journal of obstetrics, gynecology, and reproductive biology
Author(s)
Delomenie M., Bonsang-Kitzis H., Bats A.S., Ngo C., Balaya V., Xuan HTN, Koual M., Mathevet P., Lecuru F.
ISSN
1872-7654 (Electronic)
ISSN-L
0301-2115
Publication state
Published
Issued date
10/2019
Peer-reviewed
Oui
Volume
241
Pages
71-76
Language
english
Notes
Publication types: Journal Article ; Systematic Review
Publication Status: ppublish
Abstract
Lymph node macroscopic involvement in cervical cancer is a well-known prognostic factor, allows the gynecologic-oncologist to identify women at increased risk for recurrence. Since the development of sentinel node biopsy, micrometastases (MMs) and Isolated Tumor Cells (ICTs) have been increasingly identified in cervical cancer, however their prognostic value and treatment are still controversial. We reviewed the literature (MEDLINE and EMBASE database analysis) from inception up to January 2019, concerning the incidence of lymph nodes MMs and ITCs in cervical cancer, their controversial histologic and molecular biology definition, their anatomic distribution, the role of frozen section and the prognostic value and treatment options for women diagnosed with lymph nodes MMs/ITCs.
Keywords
Female, Humans, Lymph Nodes/pathology, Neoplasm Micrometastasis, Prognosis, Uterine Cervical Neoplasms/diagnosis, Uterine Cervical Neoplasms/pathology, Uterine Cervical Neoplasms/therapy, Cervical cancer, Isolated tumor cells, Lymph nodes micrometastases, Review
Pubmed
Web of science
Open Access
Yes
Create date
17/09/2019 12:58
Last modification date
23/04/2024 6:01
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