Utilisation des antibiotiques pour la prevention des pneumonies bacteriennes dans les Unites de soins intensifs chirurgicaux. [Use of antibiotics for the prevention of bacterial pneumonia in surgical intensive care units]

Details

Serval ID
serval:BIB_42EED3A8A752
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Utilisation des antibiotiques pour la prevention des pneumonies bacteriennes dans les Unites de soins intensifs chirurgicaux. [Use of antibiotics for the prevention of bacterial pneumonia in surgical intensive care units]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Baumgartner  J. D., Glauser  M. P.
ISSN
0036-7672
Publication state
Published
Issued date
05/1987
Peer-reviewed
Oui
Volume
117
Number
19
Pages
707-11
Notes
English Abstract
Journal Article --- Old month value: May 9
Abstract
Bacterial pneumonia is responsible for high mortality in surgical intensive care patients which is partly attributable to a high incidence of gram-negative bacillary pneumonia. In these patients alterations to epithelial cell surfaces promote colonization of the oropharynx by gram-negative bacilli. The alterations are directly related to the severity of the patients' underlying disease and not to the hospital environment. Prospective studies on prophylactic administration of antibiotics to decrease the incidence of nosocomial pneumonia are reviewed. In these studies antibiotic have been administered either locally in the respiratory tract or systemically by the i.v. route. In both cases a moderate decrease in the incidence of pneumonia was observed, but selection of resistant bacteria occurred. Pneumonia appearing despite antibiotic prophylaxis was difficult to treat and had a high mortality. Therefore, local or intravenous antibiotic administration for routine prophylaxis of pneumonia seems to do more harm than good in patients from intensive care units.
Keywords
Administration, Topical Anti-Bacterial Agents/administration & dosage/*therapeutic use Bacterial Infections/*prevention & control Gram-Negative Bacteria Humans Infusions, Intravenous Intensive Care Units Pneumonia/etiology/*prevention & control Postoperative Complications/*prevention & control
Pubmed
Web of science
Create date
19/01/2008 18:12
Last modification date
20/08/2019 13:45
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