Article: article from journal or magazin.
Zavisimost' mezhdy vnutrikletochnym soderzhaniem 1-metil-3-izobutilksantina i pronitsaemost'iu dlia vody stenki mochevogo puzyria liagushki [The relationship between the intracellular content of 1-methyl-3-isobutylxanthine and the permeability for water of the bladder wall in the frog].
Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova
Publication types: Comparative Study ; English Abstract ; Journal Article Publication Status: ppublish
The data obtained show a direct interrelationship between the concentration of MIBX in cells and an increase of osmotic permeability. The method of determination of intracellular concentration of the MIBX using [3H]-MIBX, was developed, and the way to obtain radioactive MIBX described. The used approach permits to take into consideration functional changes as related to the intracellular concentration of inhibiting agents.
1-Methyl-3-isobutylxanthine/pharmacology, 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors, Animals, Cell Membrane Permeability/drug effects, Cell Membrane Permeability/physiology, Cyclic AMP/pharmacology, Dose-Response Relationship, Drug, Osmosis/drug effects, Rana temporaria, Theophylline/analogs & derivatives, Tritium/diagnostic use, Urinary Bladder/drug effects, Urinary Bladder/physiology, Water/metabolism
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