Drug and toxin-induced bile duct disorders.

Détails

ID Serval
serval:BIB_4251DAE73A49
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Drug and toxin-induced bile duct disorders.
Périodique
Journal of Gastroenterology and Hepatology
Auteur(s)
Geubel A.P., Sempoux C.L.
ISSN
0815-9319 (Print)
ISSN-L
0815-9319
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
15
Numéro
11
Pages
1232-1238
Langue
anglais
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublish
Résumé
Various drugs of toxins have been implicated in the development of a particular form of liver damage predominantly involving the bile ducts. Such liver toxicity is often associated with a clinical picture of prolonged cholestasis and may even evolve in rare instances, into the full picture of the vanishing bile duct syndrome, eventually complicated with biliary cirrhosis. Drug and toxins potentially responsible for bile duct injury are reviewed as well as the characteristics of its clinical presentation. The pathophysiologic aspects of the syndrome are also reviewed including recent data, which are strongly in favor of the role of a genetic predisposition.
Mots-clé
Bile Duct Diseases/chemically induced, Bile Duct Diseases/diagnosis, Cholestasis/chemically induced, Drug-Induced Liver Injury, Drug-Related Side Effects and Adverse Reactions/diagnosis, Drug-Related Side Effects and Adverse Reactions/physiopathology, Genetic Predisposition to Disease, Humans, Syndrome, Toxins, Biological
Pubmed
Web of science
Création de la notice
20/10/2016 17:33
Dernière modification de la notice
03/03/2018 16:37
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