First episode schizophrenia and schizoaffective disorder: A psychiatric nosology

Détails

ID Serval
serval:BIB_4200D4BE5E3B
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Titre
First episode schizophrenia and schizoaffective disorder: A psychiatric nosology
Titre de la conférence
From neurobiology to public policy. Abstracts of the 8th International Conference on Early Psychosis: From Neurobiology to Public Policy
Auteur(s)
Cotton Sue, Lambert Martin, Schimmelmann Benno, Mackinnon Andrew, Gleeson John, Berk Michael, Hides Leanne, Chanen Andrew, Scott James, McGorry Patrick, Conus Philippe
Adresse
Oct 11-13, 2012; San Francisco, CA, United States
ISBN
1751-7893
ISSN-L
1751-7885
Statut éditorial
Publié
Date de publication
2012
Volume
6
Série
Early Intervention in Psychiatry
Pages
53
Langue
anglais
Résumé
A nosological issue that has yet to be resolved relates to the diagnostic and clinical overlap of schizophrenia and schizoaffective disorder. Thus, the aim of this study was to compare, within a treated epidemiological cohort of first episode patients, the clinical characteristics of patients with schizophrenia (FES) or schizoaffective disorder (FESA). Medical fi le audit methodology was employed to collect information on 704 first episode psychosis patients (FEP), among which 283 patients had a fi nal diagnosis of FES and 64 patients with a fi nal diagnosis of FESA. These patients were treated at the Early Psychosis Prevention and Intervention Centre (EPPIC), Melbourne, Australia. Patients with FES were signifi cantly more likely to have a longer prodrome (P = .020), longer duration of untreated psychosis (P < .001), and earlier age of onset (P = .004) compared to FESA. At service entry, FESA patients had more severe levels of psychopathology (P = .020), which was due to the presence of manic symptoms (P < .001); consequently, requiring a greater number of inpatient admissions (P = .017). At discharge, depressive symptoms were more severe in those with FESA (P = .011). There are signifi cant differences in the phenomenology of schizophrenia and schizoaffective disorder during early illness course; supporting the notion that these are two discernable disorders.
Web of science
Création de la notice
12/12/2012 17:07
Dernière modification de la notice
20/08/2019 14:43
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