Major coagulation disorders when using aprotinin--observations on a case

Détails

ID Serval
serval:BIB_41D8FF7DCE08
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Major coagulation disorders when using aprotinin--observations on a case
Périodique
Thoracic and Cardiovascular Surgeon
Auteur(s)
Gersbach  P., Lammle  B., Schupbach  P., Muhlemann  W., Althaus  U.
ISSN
0171-6425 (Print)
Statut éditorial
Publié
Date de publication
08/1991
Volume
39
Numéro
4
Pages
196-8
Notes
Case Reports
Journal Article --- Old month value: Aug
Résumé
Intraoperative application of the proteinase inhibitor aprotinin allows to drastically reduce blood loss during and after cardiopulmonary bypass operation. The side effects of this therapy (if any) have not been systematically registered and a possible interaction with heparin is not excluded. Such an interaction seems to have occurred in one of our patients. He developed a resistance to heparin shortly after prophylactic administration of aprotinin and maintained it for about one hour after discontinuation of the aprotinin. Prophylactic and therapeutic implications of this observation are briefly exposed.
Mots-clé
Aged Aprotinin/*adverse effects Blood Coagulation Disorders/*chemically induced Cardiac Surgical Procedures Heparin/administration & dosage Humans Male Postoperative Complications/chemically induced
Pubmed
Web of science
Création de la notice
28/01/2008 10:17
Dernière modification de la notice
03/03/2018 16:34
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