Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: the Pediatric Rheumatology International Trials Organization multinational quality of life cohort study

Détails

ID Serval
serval:BIB_41B6FDFA3F6F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: the Pediatric Rheumatology International Trials Organization multinational quality of life cohort study
Périodique
Arthritis and Rheumatism
Auteur(s)
Oliveira  S., Ravelli  A., Pistorio  A., Castell  E., Malattia  C., Prieur  A. M., Saad-Magalhaes  C., Murray  K. J., Bae  S. C., Joos  R., Foeldvari  I., Duarte-Salazar  C., Wulffraat  N., Lahdenne  P., Dolezalova  P., de Inocencio  J., Kanakoudi-Tsakalidou  F., Hofer  M., Nikishina  I., Ozdogan  H., Hashkes  P. J., Landgraf  J. M., Martini  A., Ruperto  N.
ISSN
0004-3591
Statut éditorial
Publié
Date de publication
02/2007
Peer-reviewed
Oui
Volume
57
Numéro
1
Pages
35-43
Notes
Journal Article Multicenter Study Research Support, Non-U.S. Gov't --- Old month value: Feb 15
Résumé
OBJECTIVE: To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA). METHODS: In this multinational, multicenter, cross-sectional study, HRQOL of patients with JIA was assessed through the Child Health Questionnaire (CHQ) and was compared with that of healthy children of similar age from the same geographic area. Potential determinants of HRQOL included demographic data, physician's and parent's global assessments, measures of joint inflammation, Childhood Health Assessment Questionnaire (CHAQ), and erythrocyte sedimentation rate. RESULTS: A total of 6,639 participants (3,324 with JIA and 3,315 healthy) were enrolled from 32 countries. The mean +/- SD physical and psychosocial summary scores of the CHQ were significantly lower in patients with JIA than in healthy children (physical: 44.5 +/- 10.6 versus 54.6 +/- 4.0, P < 0.0001; psychosocial: 47.6 +/- 8.7 versus 51.9 +/- 7.5, P < 0.0001), with the physical well-being domain being most impaired. Patients with persistent oligoarthritis had better HRQOL compared with other subtypes, whereas HRQOL was similar across patients with systemic arthritis, polyarthritis, and extended oligoarthritis. A CHAQ score >1 and a pain intensity rating >3.4 cm on a 10-cm visual analog scale were the strongest determinants of poorer HRQOL in the physical and psychosocial domains, respectively. CONCLUSION: We found that patients with JIA have a significant impairment of their HRQOL compared with healthy peers, particularly in the physical domain. Physical well-being was mostly affected by the level of functional impairment, whereas the intensity of pain had the greatest influence on psychosocial health.
Mots-clé
Activities of Daily Living Adolescent Arthritis, Juvenile Rheumatoid/*complications/*psychology/therapy Case-Control Studies Child Child, Preschool Cohort Studies Cross-Sectional Studies Disability Evaluation Female *Health Status Health Surveys Humans International Cooperation Male Pain/complications/etiology *Proxy Psychology *Quality of Life Severity of Illness Index
Pubmed
Web of science
Création de la notice
20/01/2008 16:23
Dernière modification de la notice
03/03/2018 16:34
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