Tuberculosis one century after R. Koch

Détails

ID Serval
serval:BIB_419B91A2E6B1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Tuberculosis one century after R. Koch
Périodique
Schweizerische Medizinische Wochenschrift
Auteur(s)
Telenti  A.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
01/1998
Volume
128
Numéro
3
Pages
80-3
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan 17
Résumé
The molecular revolution is beginning to have an impact on all aspects of tuberculosis. Work in diagnostics is expected to progress in maximizing genetic testing of mycobacteria. Drug development will benefit from recently acquired knowledge on molecular mechanisms of drug action. The availability of the complete genome of Mycobacterium tuberculosis, and better tools for genetic work with mycobacteria, will promote the development of vaccine candidates. Our work has contributed to the definition of the mechanisms of resistance to rifampin, fluoroquinolones, and ethambutol, and, using molecular analysis, to a better understanding of the epidemiology of mycobacterial infections. This overview of the direction of tuberculosis research today illustrates the impact of novel scientific approaches on the investigation of old problems.
Mots-clé
Antitubercular Agents/*therapeutic use BCG Vaccine Drug Resistance, Microbial Genetics, Microbial Genome Humans Molecular Biology Mycobacterium tuberculosis/*genetics Tuberculosis/diagnosis/*microbiology/therapy
Pubmed
Web of science
Création de la notice
25/01/2008 15:46
Dernière modification de la notice
03/03/2018 16:34
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