The airway microbiome and disease.

Détails

ID Serval
serval:BIB_40711521F541
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
The airway microbiome and disease.
Périodique
Chest
Auteur(s)
Marsland B.J., Yadava K., Nicod L.P.
ISSN
0012-3692 (Print)
ISSN-L
0012-3692
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
144
Numéro
2
Pages
632-637
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
Although traditionally thought to be sterile, accumulating evidence now supports the concept that our airways harbor a microbiome. Thus far, studies have focused upon characterizing the bacterial constituents of the airway microbiome in both healthy and diseased lungs, but what perhaps provides the greatest impetus for the exploration of the airway microbiome is that different bacterial phyla appear to dominate diseased as compared with healthy lungs. As yet, there is very limited evidence supporting a functional role for the airway microbiome, but continued research in this direction is likely to provide such evidence, particularly considering the progress that has been made in understanding host-microbe mutualism in the intestinal tract. In this review, we highlight the major advances that have been made discovering and describing the airway microbiome, discuss the experimental evidence that supports a functional role for the microbiome in health and disease, and propose how this emerging field is going to impact clinical practice.
Pubmed
Web of science
Création de la notice
13/09/2013 17:23
Dernière modification de la notice
03/03/2018 16:28
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