An inversion supergene in Drosophila underpins latitudinal clines in survival traits.

Détails

ID Serval
serval:BIB_406ED85C063C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
An inversion supergene in Drosophila underpins latitudinal clines in survival traits.
Périodique
Journal of evolutionary biology
Auteur(s)
Durmaz E., Benson C., Kapun M., Schmidt P., Flatt T.
ISSN
1420-9101 (Electronic)
ISSN-L
1010-061X
Statut éditorial
Publié
Date de publication
09/2018
Peer-reviewed
Oui
Volume
31
Numéro
9
Pages
1354-1364
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
Publication Status: ppublish
Résumé
Chromosomal inversions often contribute to local adaptation across latitudinal clines, but the underlying selective mechanisms remain poorly understood. We and others have previously shown that a clinal inversion polymorphism in Drosophila melanogaster, In(3R)Payne, underpins body size clines along the North American and Australian east coasts. Here, we ask whether this polymorphism also contributes to clinal variation in other fitness-related traits, namely survival traits (lifespan, survival upon starvation and survival upon cold shock). We generated homokaryon lines, either carrying the inverted or standard chromosomal arrangement, isolated from populations approximating the endpoints of the North American cline (Florida, Maine) and phenotyped the flies at two growth temperatures (18 °C, 25 °C). Across both temperatures, high-latitude flies from Maine lived longer and were more stress resistant than low-latitude flies from Florida, as previously observed. Interestingly, we find that this latitudinal pattern is partly explained by the clinal distribution of the In(3R)P polymorphism, which is at ~ 50% frequency in Florida but absent in Maine: inverted karyotypes tended to be shorter-lived and less stress resistant than uninverted karyotypes. We also detected an interaction between karyotype and temperature on survival traits. As In(3R)P influences body size and multiple survival traits, it can be viewed as a 'supergene', a cluster of tightly linked loci affecting multiple complex phenotypes. We conjecture that the inversion cline is maintained by fitness trade-offs and balancing selection across geography; elucidating the mechanisms whereby this inversion affects alternative, locally adapted phenotypes across the cline is an important task for future work.
Mots-clé
Adaptation, Physiological/genetics, Animals, Body Size/genetics, Chromosome Inversion, Drosophila melanogaster/genetics, Florida, Genetic Fitness, Karyotype, Longevity, Maine, Phenotype, Polymorphism, Genetic, Selection, Genetic, Temperature, Drosophila melanogaster , adaptation, clines, inversion, life history, supergene, survival, temperature
Pubmed
Web of science
Création de la notice
23/07/2018 16:42
Dernière modification de la notice
14/10/2019 5:09
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