Trabeculectomy with mitomycin C in glaucoma associated with uveitis

Details

Serval ID
serval:BIB_403081BC84FC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Trabeculectomy with mitomycin C in glaucoma associated with uveitis
Journal
Ophthalmic Surgery
Author(s)
Prata, J. A., Jr. , Neves  R. A., Minckler  D. S., Mermoud  A., Heuer  D. K.
ISSN
0022-023X (Print)
Publication state
Published
Issued date
10/1994
Volume
25
Number
9
Pages
616-20
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Sep-Oct
Abstract
Twenty-four trabeculectomies performed in 24 patients for control of uveitic glaucoma were retrospectively evaluated to analyze the effect of intraoperative application of mitomycin C (MMC) on the short-term outcome of trabeculectomy for glaucoma associated with uveitis. Success rates, postoperative levels of intraocular pressure (IOP), and complications were studied. After a mean follow up of 9.87 months (range, 3 to 27 months), 18 eyes (75%) achieved an IOP of 21 mm Hg or less without antiglaucoma medications. The same IOP level with one antiglaucoma medication was achieved in four eyes (16.6%). Statistical analysis demonstrated a significant reduction in IOP postoperatively during the period studied (P = .0001). Complications observed included exacerbation of the uveitis (12.5%), choroidal detachment (12.5%), hypotony (8.3%), postoperative shallow anterior chamber (4.2%), wound leak (4.2%), hyphema (4.2%), and macular edema (4.2%). The results of this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement of short-term trabeculectomy success rates in cases of uveitic glaucoma.
Keywords
Adolescent Adult Aged Aged, 80 and over Child Female Glaucoma/*drug therapy/etiology/*surgery Humans Intraocular Pressure Intraoperative Care Male Middle Aged Mitomycin/*administration & dosage Postoperative Complications Retrospective Studies *Trabeculectomy Treatment Outcome Uveitis/*complications
Pubmed
Web of science
Create date
28/01/2008 12:49
Last modification date
20/08/2019 13:37
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