HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)

Détails

ID Serval
serval:BIB_3FC4FC3B37DB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)
Périodique
Ocular Immunology and Inflammation
Auteur(s)
Borruat  F. X., Herbort  C. P., Spertini  F., Desarnaulds  A. B.
ISSN
0927-3948 (Print)
Statut éditorial
Publié
Date de publication
03/1998
Volume
6
Numéro
1
Pages
39-41
Notes
Journal Article --- Old month value: Mar
Résumé
BACKGROUND: Multiple evanescent white dot syndrome (MEWDS) is an acquired chorioretinal disorder of unknown etiology. We investigated the possibility that MEWDS might be related to a specific HLA subtyping. METHODS/RESULTS: Blood was obtained from nine patients affected by MEWDS. HLA-B51 was found in four of these nine patients with MEWDS. CONCLUSION: There was a 3.7-fold increased frequency of HLA-B51 in patients affected by MEWDS (relative risk 5.86). MEWDS might then be related to the presence of a specific HLA subtype, HLA-B51. However, due to the small sample size, our results need to be confirmed by further testing.
Mots-clé
HLA Antigens/*classification HLA-B Antigens/analysis Humans Reference Values Retina/pathology Retinal Diseases/*immunology/pathology Syndrome Vision Disorders/*immunology
Pubmed
Web of science
Création de la notice
28/01/2008 12:38
Dernière modification de la notice
20/08/2019 13:37
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