Article: article from journal or magazin.
HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)
Ocular Immunology and Inflammation
Journal Article --- Old month value: Mar
BACKGROUND: Multiple evanescent white dot syndrome (MEWDS) is an acquired chorioretinal disorder of unknown etiology. We investigated the possibility that MEWDS might be related to a specific HLA subtyping. METHODS/RESULTS: Blood was obtained from nine patients affected by MEWDS. HLA-B51 was found in four of these nine patients with MEWDS. CONCLUSION: There was a 3.7-fold increased frequency of HLA-B51 in patients affected by MEWDS (relative risk 5.86). MEWDS might then be related to the presence of a specific HLA subtype, HLA-B51. However, due to the small sample size, our results need to be confirmed by further testing.
HLA Antigens/*classification HLA-B Antigens/analysis Humans Reference Values Retina/pathology Retinal Diseases/*immunology/pathology Syndrome Vision Disorders/*immunology
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