Veränderung von Inzidenz und Mortalität von Kopf-Hals-Malignomen in Rheinland-Pfalz, 2000-2009 [Changes in Incidence and Mortality Trends of Head and Neck Cancer in Rhineland-Palatinate, 2000-2009].

Details

Serval ID
serval:BIB_3FB6E1CD99E3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Veränderung von Inzidenz und Mortalität von Kopf-Hals-Malignomen in Rheinland-Pfalz, 2000-2009 [Changes in Incidence and Mortality Trends of Head and Neck Cancer in Rhineland-Palatinate, 2000-2009].
Journal
Laryngo- Rhino- Otologie
Author(s)
Bayer O., Krüger M., Koutsimpelas D., Emrich K., Ressing M., Zeissig S.R., Simon C., Singer S.
ISSN
1438-8685 (Electronic)
ISSN-L
0935-8943
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
94
Number
7
Pages
451-458
Language
german
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
BACKGROUND: Epidemiological data on HNC are often reported aggregated despite their anatomical and histological heterogeneity. In Germany, few studies have analyzed incidence and mortality trends separately for specific anatomic sites. Furthermore, little is known about whether the incidence of HPV-associated tumour entities of the head and neck region has increased.
METHODS: Based on cancer registry data from Rhineland-Palatinate from 2000 to 2009, age-standardized incidence and mortality rates were calculated for all HNC sites and localisation groups that might be HPV-associated according to the literature. Trends were analyzed by Joinpoint regression and reported as the annual percentage change (APC).
RESULTS: Throughout the study period, 8 055 incident cases and 3 177 deaths were identified. The incidence rates of overall HNC increased among women (APC:+2.2%) and declined slightly among men (- 0.9%). Significantly increasing incidence rates among women were seen for tumours of the oral cavity (+2.7%) and the oropharynx (+3.6%). Among men, a significant decrease in incidence rates for tumours of the hypopharynx (-3.4%) and the larynx (-2.7%) are noteworthy. Cancers at HPV-associated sites showed increased incidence rates in men (+3.3%) and women (+4.3%). A decrease in mortality was found for tumours of the larynx in both sexes (-5.8% men,-9.1% women).
CONCLUSIONS: A detailed analysis by localisation of HNC showed significant and often opposing trends for men and women regarding incidence and mortality.
Keywords
Adult, Aged, Cross-Sectional Studies, Female, Germany, Humans, Incidence, Male, Middle Aged, Otorhinolaryngologic Neoplasms/epidemiology, Otorhinolaryngologic Neoplasms/mortality, Registries, Sex Factors, Survival Rate/trends
Pubmed
Web of science
Create date
24/07/2015 16:58
Last modification date
20/08/2019 13:37
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