Internal-mammary coronary artery grafts: is their superiority also due to a basically intact endothelium?

Détails

ID Serval
serval:BIB_3F4BB85B34F8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Internal-mammary coronary artery grafts: is their superiority also due to a basically intact endothelium?
Périodique
Thoracic and Cardiovascular Surgeon
Auteur(s)
Lehmann  K. H., von Segesser  L., Muller-Glauser  W., Siebenmann  R., Schneider  K., Luscher  T. F., Turina  M.
ISSN
0171-6425
Statut éditorial
Publié
Date de publication
06/1989
Peer-reviewed
Oui
Volume
37
Numéro
3
Pages
187-9
Notes
Journal Article --- Old month value: Jun
Résumé
The internal mammary artery (IMA) is a superior conduit for coronary artery revascularization and many factors have been suggested for explanation of this superiority. IMA and saphenous vein grafts have been systematically analysed with scanning electron microscopy (SEM) in a series of 11 patients undergoing coronary artery revascularization. At the time of implantation endothelial damage is almost absent in internal-mammary-artery (IMA) grafts; small areas of exposed subendothelial matrix may be present but are essentially non-thrombogenic as reflected by the lack of clots in these areas. In contrast the endothelium of harvested human saphenous veins (SV) shows large thrombogenic defects with exposed collagenous fibrils. The extent and deepness of the defects deteriorated in the period between removal of the vein and its attachment to the aorta. We conclude that long-term superiority of IMA grafts may also be due to the lack of primary intimal defects.
Mots-clé
Adult Aged *Coronary Artery Bypass Endothelium, Vascular/*physiology/ultrastructure Female Humans Male Mammary Arteries/*transplantation Microscopy, Electron, Scanning Middle Aged Saphenous Vein/transplantation/ultrastructure Thoracic Arteries/*transplantation
Pubmed
Web of science
Création de la notice
14/02/2008 15:16
Dernière modification de la notice
03/03/2018 16:25
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