Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Bilateral Krukenberg tumor of the ovary during pregnancy
European Journal of Gynaecological Oncology
This case report concerns a 35-year-old woman suffering from gravidic cholestasis, thrombocytosis and iterative vomiting episodes who underwent an elective cesarean section at week 35 because of recent herpetic vulvitis. Large bilateral ovarian tumors were observed which were interpreted as pregnancy luteomas. Nevertheless a biopsy of the right ovary was performed. Histologic examination revealed massive luteinization of the ovarian stroma. In addition, large tumor cells were found dispersed throughout the ovary as well as in vascular spaces as either isolated or clustered signet-ring cells. In search of the primary tumor, gastroscopy revealed a gastric ulcer in the antrum. The biopsies of the ulcer margins as well as those taken at distance demonstrated signet-ring cells in the lamina propria. Bilateral salpingo-oophorectomy and total gastrectomy were performed. In spite of postoperative chemotherapy, the patient died of disease 5 months after diagnosis.
Adult Female Humans Krukenberg Tumor/pathology/*secondary Luteoma/*pathology Ovarian Neoplasms/pathology/*secondary Pregnancy Pregnancy Complications, Neoplastic/*pathology Stomach Neoplasms/*pathology Stomach Ulcer/pathology
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