Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals.

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_3DDAB3B39B65
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals.
Journal
Open forum infectious diseases
Author(s)
Ragozzino S., Goldenberger D., Wright P.R., Zimmerli S., Mühlethaler K., Neofytos D., Riat A., Boggian K., Nolte O., Conen A., Fankhauser H., Schreiber P.W., Zbinden R., Lamoth F., Khanna N.
ISSN
2328-8957 (Print)
ISSN-L
2328-8957
Publication state
Published
Issued date
02/2022
Peer-reviewed
Oui
Volume
9
Number
2
Pages
ofab638
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non-fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the "environmental" mutation TR <sub>34</sub> /L98H in the cyp51A gene.
Keywords
Aspergillus fumigatus, TR34/L98H mutation, azole resistance, cyp51A gene, non-fumigatus Aspergillus spp
URN
urn:nbn:ch:serval-BIB_3DDAB3B39B658
OAI-PMH
oai:serval.unil.ch:BIB_3DDAB3B39B65
DOI
10.1093/ofid/ofab638
Pubmed
35111868
Web of science
000761458900033
Open Access
Yes
Create date
12/02/2022 15:07
Last modification date
23/11/2022 7:09
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