Cell polarity: posterior Par-1 prevents proteolysis.
Details
Serval ID
serval:BIB_392233F0AE95
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
Title
Cell polarity: posterior Par-1 prevents proteolysis.
Journal
Current biology
ISSN
0960-9822 (Print)
ISSN-L
0960-9822
Publication state
Published
Issued date
23/07/2002
Peer-reviewed
Oui
Volume
12
Number
14
Pages
R479-81
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.
Keywords
Animals, Caenorhabditis elegans Proteins, Cell Polarity, Drosophila/embryology, Drosophila Proteins/genetics, Drosophila Proteins/metabolism, Hydrolysis, Phosphorylation, Protein Serine-Threonine Kinases/metabolism, Protein Serine-Threonine Kinases/physiology, RNA, Messenger/genetics
Pubmed
Web of science
Open Access
Yes
Create date
18/03/2008 10:36
Last modification date
05/09/2024 9:00