Cell polarity: posterior Par-1 prevents proteolysis.
Details
Serval ID
serval:BIB_392233F0AE95
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Cell polarity: posterior Par-1 prevents proteolysis.
Journal
Current Biology
ISSN
0960-9822[print], 0960-9822[linking]
Publication state
Published
Issued date
07/2002
Volume
12
Number
14
Pages
R479-R481
Language
english
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Abstract
The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.
Keywords
Animals, Caenorhabditis elegans Proteins, Cell Polarity, Drosophila/embryology, Drosophila Proteins/genetics, Drosophila Proteins/metabolism, Hydrolysis, Phosphorylation, Protein-Serine-Threonine Kinases/metabolism, Protein-Serine-Threonine Kinases/physiology, RNA, Messenger/genetics
Pubmed
Web of science
Open Access
Yes
Create date
18/03/2008 11:36
Last modification date
20/08/2019 14:28
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