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Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae.
Antimicrobial Agents and Chemotherapy
Waddlia chondrophila is an emerging cause of miscarriage in bovines and humans. Given the strict intracellular growth of this Chlamydia-like organism, its antibiotic susceptibility was tested by amoebal coculture, cell culture, and real-time PCR. W. chondrophila was susceptible to doxycycline and azithromycin but resistant to beta-lactams and fluoroquinolones.
Acanthamoeba castellanii/microbiology, Animals, Anti-Bacterial Agents/pharmacology, Chlamydiales/drug effects, Chlamydiales/growth & development, Drug Resistance, Bacterial, Microbial Sensitivity Tests, Quinolones/pharmacology
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