Equine secretory IgA and secretory component.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_367F25D157CC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Equine secretory IgA and secretory component.
Journal
International Archives of Allergy and Applied Immunology
Author(s)
Pahud J.J., Mach J.P.
ISSN
0020-5915 (Print)
ISSN-L
0020-5915
Publication state
Published
Issued date
1972
Volume
42
Number
2
Pages
175-186
Language
english
Abstract
A complete secretory immunologie system has been identified in the equine species. It is characterised by the presence of a secretory component either bound to secretory IgA (SigA) or remaining in the free form (FSC). The mean molecular weights of SigA, serum lgA and FSC have been estimated. The homology of the equine and human IgA classes have been demonstrated by cross-reaction with anti-human lgA antisera. A quantit ative study of equine immunoglobulins in various fluids have shown that SlgA is predominant in saliva, mature milk, nasal and lacrimal secretions, but not in colostrum. In vitro binding of human and bovine FSC is found to occur mostly with the polymerie form of equine serum lgA.
Keywords
Animals, Autoradiography, Chromatography, Gel, Colostrum/immunology, Cross Reactions, Horses/immunology, Humans, Immune Sera, Immunochemistry, Immunodiffusion, Immunoelectrophoresis, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, Immunoglobulins/analysis, Immunoglobulins/secretion, Iodine Isotopes, Milk/immunology, Mucus/immunology, Rabbits/immunology, Saliva/immunology, Tears/immunology
Pubmed
Web of science
Create date
24/04/2013 10:03
Last modification date
20/08/2019 13:24
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